{"id":356,"date":"2024-11-14T21:28:57","date_gmt":"2024-11-14T20:28:57","guid":{"rendered":"https:\/\/medaimun.de\/?page_id=356"},"modified":"2025-06-11T13:14:25","modified_gmt":"2025-06-11T11:14:25","slug":"service-leistungen","status":"publish","type":"page","link":"https:\/\/medaimun.de\/en\/service-leistungen\/","title":{"rendered":"Services"},"content":{"rendered":"
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
<\/div>\n\t\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t\t
<\/div>\n\t\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t

Clinical research<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Medaimun's clinical service covers the entire spectrum of planning, execution, and evaluation of drug substances in all stages of clinical development. Medaimun specializes particularly in Phase II studies, also known as \"Proof of Concept\" studies. Our clinical service includes:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
<\/i><\/div><\/div>
\n

Consulting<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
<\/i><\/div><\/div>
\n

Protocol development<\/h3>

<\/p>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
<\/i><\/div><\/div>
\n

Patient recruitment with studienproband.de<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
<\/i><\/div><\/div>
\n

Site Service<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
<\/i><\/div><\/div>
\n

Specialized examinations<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
<\/i><\/div><\/div>
\n

Medical Writing<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t
<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Protocol development<\/h2>

Asthma Protokolle<\/h3>

Prof. Zielen, our Medical Director, is a globally recognized asthma specialist. He is an active member of the EAACI Working Group on Diagnosis and Treatment of Allergic Asthma, a contributing author of the German guidelines on pediatric asthma, and highly regarded as an expert in bronchial allergen provocation (1\u20133).<\/p>

He has developed multiple study protocols and has served as Principal Investigator (PI) or National Coordinator in numerous clinical trials.<\/p>

  1. Effects of tregalizumab on allergen-induced airway responses and airway inflammation in asthmatic patients Phase 2<\/strong> (allergic asthma in ages ranging from 18 to 65)\u00a0<\/li><\/ol>

    \u00a0 \u00a0 \u00a0 \u00a0 Sponsor: T-Balance<\/p>

    \u00a0 \u00a0 \u00a0 \u00a0 EudraCT Number: 2020-000585-41.<\/p>

    \u00a0<\/p>

    1. A prospective multicenter placebo-controlled trial to study the efficacy and safety of Tiotropium in preventing severe asthma exacerbations in partial and uncontrolled preschool asthma. TIPP-Study<\/strong> (Asthma Alter 1-5 Jahre)<\/li><\/ol>

      \u00a0 \u00a0 \u00a0 \u00a0 Sponsor: Goethe-University (IIT Prof. Zielen)<\/p>

      \u00a0 \u00a0 \u00a0 \u00a0 EudraCT Number: 2021-000190-81<\/p>

      \u00a0<\/p>

      1. Efficacy and Safety of QGE031 (Ligelizumab) versus Placebo and Omalizumab in patients aged 18-75 years with asthma<\/strong> (Asthma ages 18-75 Jahre)<\/li><\/ol>

        \u00a0 \u00a0 \u00a0 \u00a0 Sponsor T-Balance: Novartis GmbH<\/p>

        \u00a0 \u00a0 \u00a0 \u00a0 EudraCT Number:2020-000585-41.<\/p>

        \u00a0 \u00a0 \u00a0 \u00a0 A detailed analysis of the study can be found in reference 5.\u00a0<\/p>

        References:<\/strong><\/p>

        1. Medical algorithm: Diagnosis and treatment of house dust mite-driven allergic asthma.<\/strong> Schulze J, Agache I, Eguiluz-Gracia I, Trischler J, Zielen S. Allergy. 2023 May;78(5):1397-1399. doi: 10.1111\/all.15654.<\/li>
        2. EAACI position paper on the clinical use of the bronchial allergen challenge: Unmet needs and research priorities.<\/strong> Agache I, Antolin-Amerigo D, … et al. .Zielen S, Eguiluz- Gracia I. Allergy. 2022 Jun;77(6):1667-1684. doi: 10.1111\/all. 15203.<\/li>
        3. The late asthmatic reaction is in part independent from the early asthmatic reactions. <\/strong>Zielen S, Alemdar O, Wimmers A, Gronau L, Duecker R, Hutter M, Trischler J, Monchy JG, Schubert R. Int J Mol Sci. 2025 Feb 27;26(5):2088. doi: 10.3390\/ijms26052088.<\/li>
        4. Dual role of microRNA-146a in experimental inflammation in human pulmonary epithelial and immune cells and expression in inflammatory lung diseases. <\/strong>Gronau L, Duecker RP, Jerkic SP, Eickmeier O, Trischler J, Chiocchetti AG, Blumchen K, Zielen S, Schubert R. Int J Mol Sci. 2024 Jul 13;25(14):7686. doi: 10.3390\/ijms25147686.<\/li>
        5. Ligelizumab treatment for severe asthma: learnings from the clinical development programme.<\/strong> Trischler J, Bottoli I, Janocha R, Heusser C, Jaumont X, Lowe P, Gautier A, Pethe A, Woessner R, Zerwes HG, Zielen S. Clin Transl Immunology. 2021 Mar 15;10(3):e1255. doi: 10.1002\/cti2.1255.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t
          \n\t\t\t\t\t

          Medical consulting<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
          \n\t\t\t\t\t\t\t\t\t

          We provide our clients with advice on all matters related to infectiology, pulmonology, and allergology. Our consulting services include:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          <\/i><\/div><\/div>
          \n

          Consulting across all phases of product development<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          <\/i><\/div><\/div>
          \n

          Scientific consulting<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          <\/i><\/div><\/div>
          \n

          Medical consulting<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          <\/i><\/div><\/div>
          \n

          Approval processes support<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          <\/i><\/div><\/div>
          \n

          Preparation of expert assessments<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          <\/i><\/div><\/div>
          \n

          Literature research<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          <\/i><\/div><\/div>
          \n

          Organization of training, seminars, and conferences<\/h3>\n <\/div>\n \n <\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t
          \n\t\t\t
          \n\t\t\t\t\t\t
          \n\t\t\t\t\t

          Schedule an appointment<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
          \n\t\t\t\t\t\t\t\t\t

          Schedule your appointment with Prof. Dr. Zielen online<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

          \n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tSchedule an appointment<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

          Klinische Forschung Der klinische Service von Medaimun umfasst das gesamte Spektrum der Planung, Durchf\u00fchrung und Bewertung von Arzneimittelsubstanzen in allen Abschnitten der klinischen Entwicklung, spezialisiert ist Medaimun vor allem auf Phase II Studien sogenannten \u201eProof of Concept\u201c Studien. Unser klinischer Service umfasst: Beratung Protokoll Entwicklung Patientenrekrutierung mit Studienproband.de Site Service Spezialuntersuchungen Medical Writing Protokollentwicklung Asthma […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-356","page","type-page","status-publish","hentry"],"yoast_head":"\nService Leistungen - Medaimun<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medaimun.de\/en\/service-leistungen\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Service Leistungen - Medaimun\" \/>\n<meta property=\"og:description\" content=\"Klinische Forschung Der klinische Service von Medaimun umfasst das gesamte Spektrum der Planung, Durchf\u00fchrung und Bewertung von Arzneimittelsubstanzen in allen Abschnitten der klinischen Entwicklung, spezialisiert ist Medaimun vor allem auf Phase II Studien sogenannten \u201eProof of Concept\u201c Studien. Unser klinischer Service umfasst: Beratung Protokoll Entwicklung Patientenrekrutierung mit Studienproband.de Site Service Spezialuntersuchungen Medical Writing Protokollentwicklung Asthma […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medaimun.de\/en\/service-leistungen\/\" \/>\n<meta property=\"og:site_name\" content=\"Medaimun\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-11T11:14:25+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medaimun.de\\\/de\\\/service-leistungen\\\/\",\"url\":\"https:\\\/\\\/medaimun.de\\\/de\\\/service-leistungen\\\/\",\"name\":\"Service Leistungen - Medaimun\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medaimun.de\\\/#website\"},\"datePublished\":\"2024-11-14T20:28:57+00:00\",\"dateModified\":\"2025-06-11T11:14:25+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/medaimun.de\\\/de\\\/service-leistungen\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/medaimun.de\\\/de\\\/service-leistungen\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/medaimun.de\\\/de\\\/service-leistungen\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/medaimun.de\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Service Leistungen\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/medaimun.de\\\/#website\",\"url\":\"https:\\\/\\\/medaimun.de\\\/\",\"name\":\"Medaimun\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/medaimun.de\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Service Leistungen - Medaimun","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medaimun.de\/en\/service-leistungen\/","og_locale":"en_US","og_type":"article","og_title":"Service Leistungen - Medaimun","og_description":"Klinische Forschung Der klinische Service von Medaimun umfasst das gesamte Spektrum der Planung, Durchf\u00fchrung und Bewertung von Arzneimittelsubstanzen in allen Abschnitten der klinischen Entwicklung, spezialisiert ist Medaimun vor allem auf Phase II Studien sogenannten \u201eProof of Concept\u201c Studien. Unser klinischer Service umfasst: Beratung Protokoll Entwicklung Patientenrekrutierung mit Studienproband.de Site Service Spezialuntersuchungen Medical Writing Protokollentwicklung Asthma […]","og_url":"https:\/\/medaimun.de\/en\/service-leistungen\/","og_site_name":"Medaimun","article_modified_time":"2025-06-11T11:14:25+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/medaimun.de\/de\/service-leistungen\/","url":"https:\/\/medaimun.de\/de\/service-leistungen\/","name":"Service Leistungen - Medaimun","isPartOf":{"@id":"https:\/\/medaimun.de\/#website"},"datePublished":"2024-11-14T20:28:57+00:00","dateModified":"2025-06-11T11:14:25+00:00","breadcrumb":{"@id":"https:\/\/medaimun.de\/de\/service-leistungen\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/medaimun.de\/de\/service-leistungen\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/medaimun.de\/de\/service-leistungen\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/medaimun.de\/"},{"@type":"ListItem","position":2,"name":"Service Leistungen"}]},{"@type":"WebSite","@id":"https:\/\/medaimun.de\/#website","url":"https:\/\/medaimun.de\/","name":"Medaimun","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/medaimun.de\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/pages\/356","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/comments?post=356"}],"version-history":[{"count":3,"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/pages\/356\/revisions"}],"predecessor-version":[{"id":5895,"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/pages\/356\/revisions\/5895"}],"wp:attachment":[{"href":"https:\/\/medaimun.de\/en\/wp-json\/wp\/v2\/media?parent=356"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}